Episodic ataxia is diagnosed using tests such as a neurological examination, electromyography (EMG), and genetic testing.
After diagnosis, EA is typically treated with anticonvulsant/antiseizure medication. Acetazolamide is one of the most common drugs in the treatment of EA1 and EA2, though it’s more effective in treating EA2.
Alternative medications used to treat EA1 include carbamazepine and valproic acid. In EA2, other drugs include flunarizine and dalfampridine (4-aminopyridine).
Your doctor or neurologist might prescribe additional drugs to treat other symptoms associated with EA. For instance, amifampridine (3,4-diaminopyridine) has proved useful in treating nystagmus.
In some cases, physical therapy may be used alongside medication to improve strength and mobility. People who have ataxia might also consider diet and lifestyle changes to avoid triggers and maintain overall health.
Additional clinical trials are required to improve treatment options for people with EA.